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Kisspeptin Restores Pulsatile LH Secretion in Patients with Neurokinin B Signaling Deficiencies: Physiological, Pathophysiological and Therapeutic Implications
Pulsatile gonadotropin-releasing hormone (GnRH) is crucial to normal reproductive function and abnormalities in pulse frequency give rise to reproductive dysfunction. Kisspeptin and neurokinin B (NKB), neuropeptides secreted by the same neuronal population in the ventral hypothalamus, have emerged r...
Autores principales: | Young, Jacques, George, Jyothis T., Tello, Javier A., Francou, Bruno, Bouligand, Jerome, Guiochon-Mantel, Anne, Brailly-Tabard, Sylvie, Anderson, Richard A., Millar, Robert P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902960/ https://www.ncbi.nlm.nih.gov/pubmed/22377698 http://dx.doi.org/10.1159/000336376 |
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