Cargando…
Control of spontaneous ovarian tumors by CD8+ T cells through NKG2D-targeted delivery of antigenic peptide
BACKGROUND: There is an urgent need to develop targeted therapies for the control of advanced stage ovarian cancer because it is the most deadly gynecologic cancer. Antigen-specific immunotherapy is a promising approach because of the potential of the immune system to specifically target tumors with...
Autores principales: | Kang, Tae Heung, Knoff, Jayne, Yang, Benjamin, Tsai, Ya-Chea, He, Liangmei, Hung, Chien-Fu, Wu, T-C |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903078/ https://www.ncbi.nlm.nih.gov/pubmed/24354786 http://dx.doi.org/10.1186/2045-3701-3-48 |
Ejemplares similares
-
Tumor-Targeted Delivery of IL-2 by NKG2D Leads to Accumulation of Antigen-Specific CD8+ T Cells in the Tumor Loci and Enhanced Anti-Tumor Effects
por: Kang, Tae Heung, et al.
Publicado: (2012) -
Buccal injection of synthetic HPV long peptide vaccine induces local and systemic antigen-specific CD8+ T-cell immune responses and antitumor effects without adjuvant
por: Yang, Ming-Chieh, et al.
Publicado: (2016) -
In vivo microRNA-155 expression influences antigen-specific T cell-mediated immune responses generated by DNA vaccination
por: Mao, Chih-Ping, et al.
Publicado: (2011) -
Creation of a Merkel cell polyomavirus small T antigen-expressing murine tumor model and a DNA vaccine targeting small T antigen
por: Gomez, Bianca, et al.
Publicado: (2013) -
Direct T Cell Activation via CD40 Ligand Generates High Avidity CD8(+) T Cells Capable of Breaking Immunological Tolerance for the Control of Tumors
por: Soong, Ruey-Shyang, et al.
Publicado: (2014)