Programmable Removal of Bacterial Strains by Use of Genome-Targeting CRISPR-Cas Systems

CRISPR (clustered regularly interspaced short palindromic repeats)-Cas (CRISPR-associated) systems in bacteria and archaea employ CRISPR RNAs to specifically recognize the complementary DNA of foreign invaders, leading to sequence-specific cleavage or degradation of the target DNA. Recent work has s...

Descripción completa

Detalles Bibliográficos
Autores principales: Gomaa, Ahmed A., Klumpe, Heidi E., Luo, Michelle L., Selle, Kurt, Barrangou, Rodolphe, Beisel, Chase L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903277/
https://www.ncbi.nlm.nih.gov/pubmed/24473129
http://dx.doi.org/10.1128/mBio.00928-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903277/
https://www.ncbi.nlm.nih.gov/pubmed/24473129
http://dx.doi.org/10.1128/mBio.00928-13

Ejemplares similares