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HTSstation: A Web Application and Open-Access Libraries for High-Throughput Sequencing Data Analysis

The HTSstation analysis portal is a suite of simple web forms coupled to modular analysis pipelines for various applications of High-Throughput Sequencing including ChIP-seq, RNA-seq, 4C-seq and re-sequencing. HTSstation offers biologists the possibility to rapidly investigate their HTS data using a...

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Detalles Bibliográficos
Autores principales: David, Fabrice P. A., Delafontaine, Julien, Carat, Solenne, Ross, Frederick J., Lefebvre, Gregory, Jarosz, Yohan, Sinclair, Lucas, Noordermeer, Daan, Rougemont, Jacques, Leleu, Marion
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903476/
https://www.ncbi.nlm.nih.gov/pubmed/24475057
http://dx.doi.org/10.1371/journal.pone.0085879
Descripción
Sumario:The HTSstation analysis portal is a suite of simple web forms coupled to modular analysis pipelines for various applications of High-Throughput Sequencing including ChIP-seq, RNA-seq, 4C-seq and re-sequencing. HTSstation offers biologists the possibility to rapidly investigate their HTS data using an intuitive web application with heuristically pre-defined parameters. A number of open-source software components have been implemented and can be used to build, configure and run HTS analysis pipelines reactively. Besides, our programming framework empowers developers with the possibility to design their own workflows and integrate additional third-party software. The HTSstation web application is accessible at http://htsstation.epfl.ch.