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Traceless Bioresponsive Shielding of Adenovirus Hexon with HPMA Copolymers Maintains Transduction Capacity In Vitro and In Vivo
Capsid surface shielding of adenovirus vectors with synthetic polymers is an emerging technology to reduce unwanted interactions of the vector particles with cellular and non-cellular host components. While it has been shown that attachment of shielding polymers allows prevention of undesired intera...
Autores principales: | Prill, Jan-Michael, Šubr, Vladimír, Pasquarelli, Noemi, Engler, Tatjana, Hoffmeister, Andrea, Kochanek, Stefan, Ulbrich, Karel, Kreppel, Florian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903484/ https://www.ncbi.nlm.nih.gov/pubmed/24475024 http://dx.doi.org/10.1371/journal.pone.0082716 |
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