Improved Diagnosis of the Transition to JAK2 (V617F) Homozygosity: The Key Feature for Predicting the Evolution of Myeloproliferative Neoplasms

Most cases of BCR-ABL1-negative myeloproliferative neoplasms (MPNs), essential thrombocythemia, polycythemia vera and primary myelofibrosis are associated with JAK2 (V617F) mutations. The outcomes of these cases are critically influenced by the transition from JAK2 (V617F) heterozygosity to homozygo...

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Detalles Bibliográficos
Autores principales: Gonzalez, Mariana Selena, De Brasi, Carlos Daniel, Bianchini, Michele, Gargallo, Patricia, Stanganelli, Carmen, Zalcberg, Ilana, Larripa, Irene Beatriz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903535/
https://www.ncbi.nlm.nih.gov/pubmed/24475114
http://dx.doi.org/10.1371/journal.pone.0086401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903535/
https://www.ncbi.nlm.nih.gov/pubmed/24475114
http://dx.doi.org/10.1371/journal.pone.0086401

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