Dual Targeting of MEK and PI3K Pathways Attenuates Established and Progressive Pulmonary Fibrosis

Pulmonary fibrosis is often triggered by an epithelial injury resulting in the formation of fibrotic lesions in the lung, which progress to impair gas exchange and ultimately cause death. Recent clinical trials using drugs that target either inflammation or a specific molecule have failed, suggestin...

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Detalles Bibliográficos
Autores principales: Madala, Satish K., Edukulla, Ramakrishna, Phatak, Mukta, Schmidt, Stephanie, Davidson, Cynthia, Acciani, Thomas H., Korfhagen, Thomas R., Medvedovic, Mario, LeCras, Timothy D., Wagner, Kimberly, Hardie, William D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903543/
https://www.ncbi.nlm.nih.gov/pubmed/24475138
http://dx.doi.org/10.1371/journal.pone.0086536

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903543/
https://www.ncbi.nlm.nih.gov/pubmed/24475138
http://dx.doi.org/10.1371/journal.pone.0086536

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