Farnesoid X Receptor Ligand Prevents Cisplatin-Induced Kidney Injury by Enhancing Small Heterodimer Partner

The farnesoid X receptor (FXR) is mainly expressed in liver, intestine and kidney. We investigated whether 6-ethyl chenodeoxycholic acid (6ECDCA), a semisynthetic derivative of chenodeoxycholic aicd (CDCA, an FXR ligand), protects against kidney injury and modulates small heterodimer partner (SHP) i...

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Detalles Bibliográficos
Autores principales: Bae, Eun Hui, Choi, Hong Sang, Joo, Soo Yeon, Kim, In Jin, Kim, Chang Seong, Choi, Joon Seok, Ma, Seong Kwon, Lee, JongUn, Kim, Soo Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903546/
https://www.ncbi.nlm.nih.gov/pubmed/24475141
http://dx.doi.org/10.1371/journal.pone.0086553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903546/
https://www.ncbi.nlm.nih.gov/pubmed/24475141
http://dx.doi.org/10.1371/journal.pone.0086553

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