Evaluation of Hyperpolarized [1-(13)C]-Pyruvate by Magnetic Resonance to Detect Ionizing Radiation Effects in Real Time

Ionizing radiation (IR) cytotoxicity is primarily mediated through reactive oxygen species (ROS). Since tumor cells neutralize ROS by utilizing reducing equivalents, we hypothesized that measurements of reducing potential using real-time hyperpolarized (HP) magnetic resonance spectroscopy (MRS) and...

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Detalles Bibliográficos
Autores principales: Sandulache, Vlad C., Chen, Yunyun, Lee, Jaehyuk, Rubinstein, Ashley, Ramirez, Marc S., Skinner, Heath D., Walker, Christopher M., Williams, Michelle D., Tailor, Ramesh, Court, Laurence E., Bankson, James A., Lai, Stephen Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903593/
https://www.ncbi.nlm.nih.gov/pubmed/24475215
http://dx.doi.org/10.1371/journal.pone.0087031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903593/
https://www.ncbi.nlm.nih.gov/pubmed/24475215
http://dx.doi.org/10.1371/journal.pone.0087031

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