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An Upregulation in the Expression of Vanilloid Transient Potential Channels 2 Enhances Hypotonicity-Induced Cytosolic Ca(2+) Rise in Human Induced Pluripotent Stem Cell Model of Hutchinson Gillford Progeria
Hutchinson-Gillford Progeria Syndrome (HGPS) is a fatal genetic disorder characterized by premature aging in multiple organs including the skin, musculoskeletal and cardiovascular systems. It is believed that an increased mechanosensitivity of HGPS cells is a causative factor for vascular cell death...
Autores principales: | Lo, Chun-Yin, Tjong, Yung-Wui, Ho, Jenny Chung-Yee, Siu, Chung-Wah, Cheung, Sin-Ying, Tang, Nelson L., Yu, Shan, Tse, Hung-Fat, Yao, Xiaoqiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903625/ https://www.ncbi.nlm.nih.gov/pubmed/24475260 http://dx.doi.org/10.1371/journal.pone.0087273 |
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