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A non-redundant function of cyclin E1 in hematopoietic stem cells

A precise balance between quiescence and proliferation is crucial for the lifelong function of hematopoietic stem cells (HSCs). Cyclins E1 and E2 regulate exit from quiescence in fibroblasts, but their role in HSCs remains unknown. Here, we report a non-redundant role for cyclin E1 in mouse HSCs. A...

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Detalles Bibliográficos
Autores principales:	Campaner, Stefano, Viale, Andrea, De Fazio, Serena, Doni, Mirko, De Franco, Francesca, D’Artista, Luana, Sardella, Domenico, Pelicci, Pier Giuseppe, Amati, Bruno
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2013
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903717/ https://www.ncbi.nlm.nih.gov/pubmed/24091730 http://dx.doi.org/10.4161/cc.26584

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