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Using single cell sequencing data to model the evolutionary history of a tumor

BACKGROUND: The introduction of next-generation sequencing (NGS) technology has made it possible to detect genomic alterations within tumor cells on a large scale. However, most applications of NGS show the genetic content of mixtures of cells. Recently developed single cell sequencing technology ca...

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Detalles Bibliográficos
Autores principales: Kim, Kyung In, Simon, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903814/
https://www.ncbi.nlm.nih.gov/pubmed/24460695
http://dx.doi.org/10.1186/1471-2105-15-27