p53 Regulation by TRP2 Is Not Pervasive in Melanoma

p53 is a central tumor suppressor protein and its inhibition is believed to be a prerequisite for cancer development. In approximately 50% of all malignancies this is achieved by inactivating mutations in the p53 gene. However, in several cancer entities, including melanoma, p53 mutations are rare....

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Detalles Bibliográficos
Autores principales: Houben, Roland, Schmid, Corinna P., Maier, Melissa, Wobser, Marion, Motschenbacher, Stephanie, Becker, Jürgen C., Vetter-Kauczok, Claudia S., Weyandt, Gerhard, Hesbacher, Sonja, Haferkamp, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903882/
https://www.ncbi.nlm.nih.gov/pubmed/24475287
http://dx.doi.org/10.1371/journal.pone.0087440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903882/
https://www.ncbi.nlm.nih.gov/pubmed/24475287
http://dx.doi.org/10.1371/journal.pone.0087440

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