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Cell type-specific and time-dependent light exposure contribute to silencing in neurons expressing Channelrhodopsin-2
Channelrhodopsin-2 (ChR2) has quickly gained popularity as a powerful tool for eliciting genetically targeted neuronal activation. However, little has been reported on the response kinetics of optogenetic stimulation across different neuronal subtypes. With excess stimulation, neurons can be driven...
Autores principales: | Herman, Alexander M, Huang, Longwen, Murphey, Dona K, Garcia, Isabella, Arenkiel, Benjamin R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904216/ https://www.ncbi.nlm.nih.gov/pubmed/24473077 http://dx.doi.org/10.7554/eLife.01481 |
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