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Metformin modulates hyperglycaemia-induced endothelial senescence and apoptosis through SIRT1

Background and Purpose: Endothelial dysfunction can be detected at an early stage in the development of diabetes-related microvascular disease and is associated with accelerated endothelial senescence and ageing. Hyperglycaemia-induced oxidative stress is a major contributing factor to the developme...

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Detalles Bibliográficos
Autores principales:	Arunachalam, Gnanapragasam, Samuel, Samson Mathews, Marei, Isra, Ding, Hong, Triggle, Chris R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & sons 2014
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904269/ https://www.ncbi.nlm.nih.gov/pubmed/24372553 http://dx.doi.org/10.1111/bph.12496

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