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Reduced migration of MLH1 deficient colon cancer cells depends on SPTAN1

INTRODUCTION: Defects in the DNA mismatch repair (MMR) protein MLH1 are frequently observed in sporadic and hereditary colorectal cancers (CRC). Affected tumors generate much less metastatic potential than the MLH1 proficient forms. Although MLH1 has been shown to be not only involved in postreplica...

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Detalles Bibliográficos
Autores principales:	Hinrichsen, Inga, Ernst, Benjamin Philipp, Nuber, Franziska, Passmann, Sandra, Schäfer, Dieter, Steinke, Verena, Friedrichs, Nicolaus, Plotz, Guido, Zeuzem, Stefan, Brieger, Angela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904401/ https://www.ncbi.nlm.nih.gov/pubmed/24456667 http://dx.doi.org/10.1186/1476-4598-13-11

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