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The Function of the Exocyst is Regulated by Effector Phosphorylation
The exocyst complex tethers vesicles at sites of fusion through interactions with small GTPases. The G-protein RalA resides on Glut4 vesicles, and binds to the exocyst after activation by insulin, but must then disengage to ensure continuous exocytosis. Here we report that after recognition of the e...
Autores principales: | Chen, Xiao-Wei, Leto, Dara, Xiao, Junyu, Goss, John, Wang, Qian, Shavit, Jordan A., Xiong, Tingting, Yu, Genggeng, Ginsburg, David, Toomre, Derek, Xu, Zhaohui, Saltiel, Alan R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904505/ https://www.ncbi.nlm.nih.gov/pubmed/21516108 http://dx.doi.org/10.1038/ncb2226 |
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