Paxillin is an intrinsic negative regulator of platelet activation in mice

BACKGROUND: Paxillin is a LIM domain protein localized at integrin-mediated focal adhesions. Although paxillin is thought to modulate the functions of integrins, little is known about the contribution of paxillin to signaling pathways in platelets. Here, we studied the role of paxillin in platelet a...

Descripción completa

Detalles Bibliográficos
Autores principales: Sakata, Asuka, Ohmori, Tsukasa, Nishimura, Satoshi, Suzuki, Hidenori, Madoiwa, Seiji, Mimuro, Jun, Kario, Kazuomi, Sakata, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Original Basic Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904695/
https://www.ncbi.nlm.nih.gov/pubmed/24383745
http://dx.doi.org/10.1186/1477-9560-12-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904695/
https://www.ncbi.nlm.nih.gov/pubmed/24383745
http://dx.doi.org/10.1186/1477-9560-12-1

Ejemplares similares