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Segmental Helical Motions and Dynamical Asymmetry Modulate Histidine Kinase Autophosphorylation

Histidine kinases (HKs) are dimeric receptors that participate in most adaptive responses to environmental changes in prokaryotes. Although it is well established that stimulus perception triggers autophosphorylation in many HKs, little is known on how the input signal propagates through the HAMP do...

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Detalles Bibliográficos
Autores principales: Mechaly, Ariel E., Sassoon, Nathalie, Betton, Jean-Michel, Alzari, Pedro M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904827/
https://www.ncbi.nlm.nih.gov/pubmed/24492262
http://dx.doi.org/10.1371/journal.pbio.1001776