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The Role of Calpain-Myosin 9-Rab7b Pathway in Mediating the Expression of Toll-Like Receptor 4 in Platelets: A Novel Mechanism Involved in α-Granules Trafficking

Toll-like receptors (TLRs) plays a critical role in innate immunity. In 2004, Aslam R. and Shiraki R. first determined that murine and human platelets express functional TLRs. Additionally, Andonegui G. demonstrated that platelets express TLR4, which contributes to thrombocytopenia. However, the und...

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Detalles Bibliográficos
Autores principales:	Tsai, Jui-Chi, Lin, Yi-Wen, Huang, Chun-Yao, Lin, Chih-Yuan, Tsai, Yi-Ting, Shih, Chun-Min, Lee, Chung-Yi, Chen, Yung-Hsiang, Li, Chi-Yuan, Chang, Nen-Chung, Lin, Feng-Yen, Tsai, Chien-Sung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904858/ https://www.ncbi.nlm.nih.gov/pubmed/24489676 http://dx.doi.org/10.1371/journal.pone.0085833

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