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A20 Is Critical for the Induction of Pam3CSK4-Tolerance in Monocytic THP-1 Cells

A20 functions to terminate Toll-like receptor (TLR)-induced immune response, and play important roles in the induction of lipopolysacchride (LPS)-tolerance. However, the molecular mechanism for Pam3CSK4-tolerance is uncertain. Here we report that TLR1/2 ligand Pam3CSK4 induced tolerance in monocytic...

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Detalles Bibliográficos
Autores principales: Hu, Jinyue, Wang, Guihua, Liu, Xueting, Zhou, Lina, Jiang, Manli, Yang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905037/
https://www.ncbi.nlm.nih.gov/pubmed/24489933
http://dx.doi.org/10.1371/journal.pone.0087528

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