Cargando…
Clinical experiences in fungal keratitis caused by Acremonium
PURPOSE: To report the predisposing risk factors, clinical presentation, management, and therapeutic outcomes of fungal keratitis caused by Acremonium. METHODS: This is a retrospective study of cases with Acremonium fungal keratitis that presented to our tertiary referral center between January 2006...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905093/ https://www.ncbi.nlm.nih.gov/pubmed/24492439 http://dx.doi.org/10.2147/OPTH.S54255 |
_version_ | 1782301288922349568 |
---|---|
author | Kim, Seong-Jae Cho, Yong-Wun Seo, Seong-Wook Kim, Sun-Joo Yoo, Ji-Myong |
author_facet | Kim, Seong-Jae Cho, Yong-Wun Seo, Seong-Wook Kim, Sun-Joo Yoo, Ji-Myong |
author_sort | Kim, Seong-Jae |
collection | PubMed |
description | PURPOSE: To report the predisposing risk factors, clinical presentation, management, and therapeutic outcomes of fungal keratitis caused by Acremonium. METHODS: This is a retrospective study of cases with Acremonium fungal keratitis that presented to our tertiary referral center between January 2006 and August 2012. Patient demographic and clinical details were determined and reported. RESULTS: Five cases of fungal keratitis from Acremonium species were identified in five patients (three males, two females). The mean age of the patients was of 73.4±5.46 years, with a mean follow-up time of 124±72 days. All patients had a history of corneal trauma with vegetable matter. Four cases were unresponsive to initial treatment (0.2% fluconazole, 0.15% amphotericin B) and required topical 5% natamycin, and, in two out of five cases, topical 1% voriconazole. CONCLUSION: The most common risk factors for Acremonium fungal keratitis was ocular trauma. When a corneal lesion is found to be unresponsive to the initial treatment, we should consider adding or substituting topical natamycin or voriconazole for treatment. |
format | Online Article Text |
id | pubmed-3905093 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-39050932014-01-30 Clinical experiences in fungal keratitis caused by Acremonium Kim, Seong-Jae Cho, Yong-Wun Seo, Seong-Wook Kim, Sun-Joo Yoo, Ji-Myong Clin Ophthalmol Case Series PURPOSE: To report the predisposing risk factors, clinical presentation, management, and therapeutic outcomes of fungal keratitis caused by Acremonium. METHODS: This is a retrospective study of cases with Acremonium fungal keratitis that presented to our tertiary referral center between January 2006 and August 2012. Patient demographic and clinical details were determined and reported. RESULTS: Five cases of fungal keratitis from Acremonium species were identified in five patients (three males, two females). The mean age of the patients was of 73.4±5.46 years, with a mean follow-up time of 124±72 days. All patients had a history of corneal trauma with vegetable matter. Four cases were unresponsive to initial treatment (0.2% fluconazole, 0.15% amphotericin B) and required topical 5% natamycin, and, in two out of five cases, topical 1% voriconazole. CONCLUSION: The most common risk factors for Acremonium fungal keratitis was ocular trauma. When a corneal lesion is found to be unresponsive to the initial treatment, we should consider adding or substituting topical natamycin or voriconazole for treatment. Dove Medical Press 2014-01-23 /pmc/articles/PMC3905093/ /pubmed/24492439 http://dx.doi.org/10.2147/OPTH.S54255 Text en © 2014 Kim et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Case Series Kim, Seong-Jae Cho, Yong-Wun Seo, Seong-Wook Kim, Sun-Joo Yoo, Ji-Myong Clinical experiences in fungal keratitis caused by Acremonium |
title | Clinical experiences in fungal keratitis caused by Acremonium |
title_full | Clinical experiences in fungal keratitis caused by Acremonium |
title_fullStr | Clinical experiences in fungal keratitis caused by Acremonium |
title_full_unstemmed | Clinical experiences in fungal keratitis caused by Acremonium |
title_short | Clinical experiences in fungal keratitis caused by Acremonium |
title_sort | clinical experiences in fungal keratitis caused by acremonium |
topic | Case Series |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905093/ https://www.ncbi.nlm.nih.gov/pubmed/24492439 http://dx.doi.org/10.2147/OPTH.S54255 |
work_keys_str_mv | AT kimseongjae clinicalexperiencesinfungalkeratitiscausedbyacremonium AT choyongwun clinicalexperiencesinfungalkeratitiscausedbyacremonium AT seoseongwook clinicalexperiencesinfungalkeratitiscausedbyacremonium AT kimsunjoo clinicalexperiencesinfungalkeratitiscausedbyacremonium AT yoojimyong clinicalexperiencesinfungalkeratitiscausedbyacremonium |