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Prevalence of frailty and its ability to predict in hospital delirium, falls, and 6-month mortality in hospitalized older patients
BACKGROUND: The prevalence and significance of frailty are seldom studied in hospitalized patients. Aim of this study is to evaluate the prevalence of frailty and to determine the extent that frailty predicts delirium, falls and mortality in hospitalized older patients. METHODS: In a prospective stu...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905102/ https://www.ncbi.nlm.nih.gov/pubmed/24393272 http://dx.doi.org/10.1186/1471-2318-14-1 |
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author | Joosten, Etienne Demuynck, Mathias Detroyer, Elke Milisen, Koen |
author_facet | Joosten, Etienne Demuynck, Mathias Detroyer, Elke Milisen, Koen |
author_sort | Joosten, Etienne |
collection | PubMed |
description | BACKGROUND: The prevalence and significance of frailty are seldom studied in hospitalized patients. Aim of this study is to evaluate the prevalence of frailty and to determine the extent that frailty predicts delirium, falls and mortality in hospitalized older patients. METHODS: In a prospective study of 220 older patients, frailty was determined using the Cardiovascular Health Study (CHS) and the Study of Osteoporotic Fracture (SOF) frailty index. Patients were classified as nonfrail, prefrail, and frail, according to the specific criteria. Covariates included clinical and laboratory parameters. Outcome variables included in hospital delirium and falls, and 6-month mortality. RESULTS: The CHS frailty index was available in all 220 patients, of which 1.5% were classified as being nonfrail, 58.5% as prefrail, and 40% as frail. The SOF frailty index was available in 204 patients, of which 16% were classified as being nonfrail, 51.5% as prefrail, and 32.5% as frail. Frailty, as identified by the CHS and SOF indexes, was a significant risk factor for 6-month mortality. However, after adjustment for multiple risk factors, frailty remained a strong independent risk factor only for the model with the CHS index (OR 4.7, 95% CI 1.7-12.8). Frailty (identified by CHS and SOF indexes) was not found to be a risk factor for delirium or falls. CONCLUSIONS: Frailty, as measured by the CHS index, is an independent risk factor for 6-month mortality. The CHS and the SOF indexes have limited value as risk assessment tools for specific geriatric syndromes (e.g., falls and delirium) in hospitalized older patients. |
format | Online Article Text |
id | pubmed-3905102 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-39051022014-01-30 Prevalence of frailty and its ability to predict in hospital delirium, falls, and 6-month mortality in hospitalized older patients Joosten, Etienne Demuynck, Mathias Detroyer, Elke Milisen, Koen BMC Geriatr Research Article BACKGROUND: The prevalence and significance of frailty are seldom studied in hospitalized patients. Aim of this study is to evaluate the prevalence of frailty and to determine the extent that frailty predicts delirium, falls and mortality in hospitalized older patients. METHODS: In a prospective study of 220 older patients, frailty was determined using the Cardiovascular Health Study (CHS) and the Study of Osteoporotic Fracture (SOF) frailty index. Patients were classified as nonfrail, prefrail, and frail, according to the specific criteria. Covariates included clinical and laboratory parameters. Outcome variables included in hospital delirium and falls, and 6-month mortality. RESULTS: The CHS frailty index was available in all 220 patients, of which 1.5% were classified as being nonfrail, 58.5% as prefrail, and 40% as frail. The SOF frailty index was available in 204 patients, of which 16% were classified as being nonfrail, 51.5% as prefrail, and 32.5% as frail. Frailty, as identified by the CHS and SOF indexes, was a significant risk factor for 6-month mortality. However, after adjustment for multiple risk factors, frailty remained a strong independent risk factor only for the model with the CHS index (OR 4.7, 95% CI 1.7-12.8). Frailty (identified by CHS and SOF indexes) was not found to be a risk factor for delirium or falls. CONCLUSIONS: Frailty, as measured by the CHS index, is an independent risk factor for 6-month mortality. The CHS and the SOF indexes have limited value as risk assessment tools for specific geriatric syndromes (e.g., falls and delirium) in hospitalized older patients. BioMed Central 2014-01-06 /pmc/articles/PMC3905102/ /pubmed/24393272 http://dx.doi.org/10.1186/1471-2318-14-1 Text en Copyright © 2014 Joosten et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Joosten, Etienne Demuynck, Mathias Detroyer, Elke Milisen, Koen Prevalence of frailty and its ability to predict in hospital delirium, falls, and 6-month mortality in hospitalized older patients |
title | Prevalence of frailty and its ability to predict in hospital delirium, falls, and 6-month mortality in hospitalized older patients |
title_full | Prevalence of frailty and its ability to predict in hospital delirium, falls, and 6-month mortality in hospitalized older patients |
title_fullStr | Prevalence of frailty and its ability to predict in hospital delirium, falls, and 6-month mortality in hospitalized older patients |
title_full_unstemmed | Prevalence of frailty and its ability to predict in hospital delirium, falls, and 6-month mortality in hospitalized older patients |
title_short | Prevalence of frailty and its ability to predict in hospital delirium, falls, and 6-month mortality in hospitalized older patients |
title_sort | prevalence of frailty and its ability to predict in hospital delirium, falls, and 6-month mortality in hospitalized older patients |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905102/ https://www.ncbi.nlm.nih.gov/pubmed/24393272 http://dx.doi.org/10.1186/1471-2318-14-1 |
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