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Structural Determinants of Unique Properties of Human IgG4-Fc()

Human IgG4, normally the least abundant of the four subclasses of IgG in serum, displays a number of unique biological properties. It can undergo heavy-chain exchange, also known as Fab-arm exchange, leading to the formation of monovalent but bispecific antibodies, and it interacts poorly with FcγRI...

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Detalles Bibliográficos
Autores principales:	Davies, Anna M., Rispens, Theo, Ooijevaar-de Heer, Pleuni, Gould, Hannah J., Jefferis, Roy, Aalberse, Rob C., Sutton, Brian J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905167/ https://www.ncbi.nlm.nih.gov/pubmed/24211234 http://dx.doi.org/10.1016/j.jmb.2013.10.039

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