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The interaction of affective with psychotic processes: A test of the effects of worrying on working memory, jumping to conclusions, and anomalies of experience in patients with persecutory delusions

Worry has traditionally been considered in the study of common emotional disorders such as anxiety and depression, but recent studies indicate that worry may be a causal factor in the occurrence and persistence of persecutory delusions. The effect of worry on processes traditionally associated with...

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Autores principales: Freeman, Daniel, Startup, Helen, Dunn, Graham, Černis, Emma, Wingham, Gail, Pugh, Katherine, Cordwell, Jacinta, Kingdon, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905189/
https://www.ncbi.nlm.nih.gov/pubmed/23871449
http://dx.doi.org/10.1016/j.jpsychires.2013.06.016
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author Freeman, Daniel
Startup, Helen
Dunn, Graham
Černis, Emma
Wingham, Gail
Pugh, Katherine
Cordwell, Jacinta
Kingdon, David
author_facet Freeman, Daniel
Startup, Helen
Dunn, Graham
Černis, Emma
Wingham, Gail
Pugh, Katherine
Cordwell, Jacinta
Kingdon, David
author_sort Freeman, Daniel
collection PubMed
description Worry has traditionally been considered in the study of common emotional disorders such as anxiety and depression, but recent studies indicate that worry may be a causal factor in the occurrence and persistence of persecutory delusions. The effect of worry on processes traditionally associated with psychosis has not been tested. The aim of the study was to examine the short-term effects of a bout of worry on three cognitive processes typically considered markers of psychosis: working memory, jumping to conclusions, and anomalous internal experience. Sixty-seven patients with persecutory delusions in the context of a non-affective psychotic disorder were randomised to a worry induction, a worry reduction, or a neutral control condition. They completed tests of the cognitive processes before and after the randomisation condition. The worry induction procedure led to a significant increase in worry. The induction of worry did not affect working memory or jumping to conclusions, but it did increase a range of mild anomalous experiences including feelings of unreality, perceptual alterations, and temporal disintegration. Worry did not affect the occurrence of hallucinations. The study shows that a period of worry causes a range of subtle odd perceptual disturbances that are known to increase the likelihood of delusions. It demonstrates an interaction between affective and psychotic processes in patients with delusions.
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spelling pubmed-39051892014-01-29 The interaction of affective with psychotic processes: A test of the effects of worrying on working memory, jumping to conclusions, and anomalies of experience in patients with persecutory delusions Freeman, Daniel Startup, Helen Dunn, Graham Černis, Emma Wingham, Gail Pugh, Katherine Cordwell, Jacinta Kingdon, David J Psychiatr Res Article Worry has traditionally been considered in the study of common emotional disorders such as anxiety and depression, but recent studies indicate that worry may be a causal factor in the occurrence and persistence of persecutory delusions. The effect of worry on processes traditionally associated with psychosis has not been tested. The aim of the study was to examine the short-term effects of a bout of worry on three cognitive processes typically considered markers of psychosis: working memory, jumping to conclusions, and anomalous internal experience. Sixty-seven patients with persecutory delusions in the context of a non-affective psychotic disorder were randomised to a worry induction, a worry reduction, or a neutral control condition. They completed tests of the cognitive processes before and after the randomisation condition. The worry induction procedure led to a significant increase in worry. The induction of worry did not affect working memory or jumping to conclusions, but it did increase a range of mild anomalous experiences including feelings of unreality, perceptual alterations, and temporal disintegration. Worry did not affect the occurrence of hallucinations. The study shows that a period of worry causes a range of subtle odd perceptual disturbances that are known to increase the likelihood of delusions. It demonstrates an interaction between affective and psychotic processes in patients with delusions. Pergamon Press 2013-12 /pmc/articles/PMC3905189/ /pubmed/23871449 http://dx.doi.org/10.1016/j.jpsychires.2013.06.016 Text en © 2013 Elsevier Ltd. https://creativecommons.org/licenses/by/3.0/This is an open access article under the CC BY license (https://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Freeman, Daniel
Startup, Helen
Dunn, Graham
Černis, Emma
Wingham, Gail
Pugh, Katherine
Cordwell, Jacinta
Kingdon, David
The interaction of affective with psychotic processes: A test of the effects of worrying on working memory, jumping to conclusions, and anomalies of experience in patients with persecutory delusions
title The interaction of affective with psychotic processes: A test of the effects of worrying on working memory, jumping to conclusions, and anomalies of experience in patients with persecutory delusions
title_full The interaction of affective with psychotic processes: A test of the effects of worrying on working memory, jumping to conclusions, and anomalies of experience in patients with persecutory delusions
title_fullStr The interaction of affective with psychotic processes: A test of the effects of worrying on working memory, jumping to conclusions, and anomalies of experience in patients with persecutory delusions
title_full_unstemmed The interaction of affective with psychotic processes: A test of the effects of worrying on working memory, jumping to conclusions, and anomalies of experience in patients with persecutory delusions
title_short The interaction of affective with psychotic processes: A test of the effects of worrying on working memory, jumping to conclusions, and anomalies of experience in patients with persecutory delusions
title_sort interaction of affective with psychotic processes: a test of the effects of worrying on working memory, jumping to conclusions, and anomalies of experience in patients with persecutory delusions
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905189/
https://www.ncbi.nlm.nih.gov/pubmed/23871449
http://dx.doi.org/10.1016/j.jpsychires.2013.06.016
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