Cargando…

Bevacizumab and fotemustine for recurrent glioblastoma: a phase II study of AINO (Italian Association of Neuro-Oncology)

The optimal combination of bevacizumab with cytotoxic or cytostatic drugs in recurrent glioblastoma is unknown. We performed a phase 2 trial of combined bevacizumab and fotemustine for patients with glioblastoma at first relapse after radiotherapy and temozolomide. The primary endpoint was 6-month p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Soffietti, Riccardo, Trevisan, Elisa, Bertero, Luca, Cassoni, Paola, Morra, Isabella, Fabrini, Maria Grazia, Pasqualetti, Francesco, Lolli, Ivan, Castiglione, Anna, Ciccone, Giovannino, Rudà, Roberta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2013
Materias:	Clinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905193/ https://www.ncbi.nlm.nih.gov/pubmed/24293233 http://dx.doi.org/10.1007/s11060-013-1317-x

Ejemplares similares

Efficacy and safety of second-line fotemustine in elderly patients with recurrent glioblastoma
por: Santoni, Matteo, et al.
Publicado: (2013)

Depatuxizumab Mafodotin (Depatux-M) Plus Temozolomide in Recurrent Glioblastoma Patients: Real-World Experience from a Multicenter Study of Italian Association of Neuro-Oncology (AINO)
por: Padovan, Marta, et al.
Publicado: (2021)

Retrospective Analysis of Bevacizumab in Combination with Fotemustine in Chinese Patients with Recurrent Glioblastoma Multiforme
por: Liu, Zhiguang, et al.
Publicado: (2015)

Review: Peering through a keyhole: liquid biopsy in primary and metastatic central nervous system tumours
por: Bertero, L., et al.
Publicado: (2019)

Activity and Safety of Bevacizumab Plus Fotemustine for Recurrent Malignant Gliomas
por: Vaccaro, V., et al.
Publicado: (2014)

Ki-67 proliferation index but not mitotic thresholds integrates the molecular prognostic stratification of lower grade gliomas
por: Duregon, Eleonora, et al.
Publicado: (2016)

Upfront Bevacizumab and Temozolomide or Fotemustine before Radiotherapy for Patients with Glioblastoma and Severe Neurological Impairment at Diagnosis
por: Bihan, Celina, et al.
Publicado: (2012)

An Overview of Fotemustine in High-Grade Gliomas: From Single Agent to Association with Bevacizumab
por: Lombardi, Giuseppe, et al.
Publicado: (2014)

Bevacizumab for the Treatment of Radiation-Induced Cerebral Necrosis: A Systematic Review of the Literature
por: Delishaj, Durim, et al.
Publicado: (2017)

Neoplastic meningitis in solid tumors: from diagnosis to personalized treatments
por: Pellerino, Alessia, et al.
Publicado: (2018)

The Effectiveness of Bevacizumab in Radionecrosis After Radiosurgery of a Single Brain Metastasis
por: Delishaj, Durim, et al.
Publicado: (2015)

Serosurveillance for Japanese encephalitis, Akabane, and Aino viruses for Thoroughbred horses in Korea
por: Yang, Dong-Kun, et al.
Publicado: (2008)

Seroepidemiology of Aino Virus in Farmed and Free-Ranging Cervids in the Republic of Korea
por: Yeh, Jung-Yong, et al.
Publicado: (2021)

Survival with dacarbazine and fotemustine in newly diagnosed glioblastoma multiforme
por: Fazeny-Dörner, B, et al.
Publicado: (2003)

Liquoral liquid biopsy in neoplastic meningitis enables molecular diagnosis and mutation tracking: a proof of concept
por: Marchiò, Caterina, et al.
Publicado: (2017)

Targeted Therapies in Rare Brain Tumours
por: Bruno, Francesco, et al.
Publicado: (2021)

Prognostic Characterization of Higher-Grade Meningiomas: A Histopathological Score to Predict Progression and Outcome
por: Bertero, Luca, et al.
Publicado: (2019)

Glioblastoma in the Elderly: Review of Molecular and Therapeutic Aspects
por: Bruno, Francesco, et al.
Publicado: (2022)

A new schedule of fotemustine in temozolomide-pretreated patients with relapsing glioblastoma
por: Addeo, Raffaele, et al.
Publicado: (2010)

Erratum to: A new schedule of fotemustine in temozolomide-pretreated patients with relapsing glioblastoma
por: Addeo, Raffaele, et al.
Publicado: (2010)

The Combination of Carmustine Wafers and Fotemustine in Recurrent Glioblastoma Patients: A Monoinstitutional Experience
por: Lombardi, Giuseppe, et al.
Publicado: (2014)

Regulation of Inflammatory and Proliferative Pathways by Fotemustine and Dexamethasone in Endometriosis
por: Genovese, Tiziana, et al.
Publicado: (2021)

Pathological prognostic markers in central nervous system solitary fibrous tumour/hemangiopericytoma: Evidence from a small series
por: Bertero, Luca, et al.
Publicado: (2018)

Clinical Significance of Molecular Alterations and Systemic Therapy for Meningiomas: Where Do We Stand?
por: Pellerino, Alessia, et al.
Publicado: (2022)

Sero-survey on Aino, Akabane, Chuzan, bovine ephemeral fever and Japanese encephalitis virus of cattle and swine in Korea
por: Lim, Seong In, et al.
Publicado: (2007)

Detection and differentiation of Schmallenberg, Akabane and Aino viruses by one-step multiplex reverse-transcriptase quantitative PCR assay
por: Lee, Ji-Hye, et al.
Publicado: (2015)

Fotemustine as second-line treatment for recurrent or progressive glioblastoma after concomitant and/or adjuvant temozolomide: a phase II trial of Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO)
por: Brandes, Alba A., et al.
Publicado: (2009)

The estimation of duration of maternally-derived antibodies against Akabane, Aino, and Chuzan virus in calves by the receiver operating characteristic analysis
por: IWAMOTO, Jiro, et al.
Publicado: (2020)

Biweekly fotemustine schedule for recurrent glioblastoma in the elderly: activity and toxicity assessment of a multicenter study
por: Addeo, Raffaele, et al.
Publicado: (2019)

Treatment of recurrent malignant gliomas with fotemustine monotherapy: impact of dose and correlation with MGMT promoter methylation
por: Fabi, Alessandra, et al.
Publicado: (2009)

Sequential administration of varying doses of dacarbazine and fotemustine in advanced malignant melanoma.
por: Lee, S. M., et al.
Publicado: (1993)

Fotemustine: A Third-Generation Nitrosourea for the Treatment of Recurrent Malignant Gliomas
por: Beauchesne, Patrick
Publicado: (2012)

NTRK Fusions in Central Nervous System Tumors: A Rare, but Worthy Target
por: Gambella, Alessandro, et al.
Publicado: (2020)

High-dose fotemustine in temozolomide-pretreated glioblastoma multiforme patients: A phase I/II trial
por: Marinelli, Alfredo, et al.
Publicado: (2018)

BSBM-12 STAT3 EXPRESSION IN BRAIN METASTASES FROM BREAST CANCER: CORRELATIONS WITH DIFFERENT MOLECULAR SUBTYPES AND CLINICAL OUTCOME
por: Pellerino, Alessia, et al.
Publicado: (2023)

Treatment of disseminated ocular melanoma with sequential fotemustine, interferon α, and interleukin 2
por: Becker, J C, et al.
Publicado: (2002)

Efficacy and safety of the third-generation chloroethylnitrosourea fotemustine for the treatment of chemorefractory T-cell lymphomas
por: Corazzelli, Gaetano, et al.
Publicado: (2011)

Combined vemurafenib and fotemustine in patients with BRAF V600 melanoma progressing on vemurafenib
por: Queirolo, Paola, et al.
Publicado: (2016)

Evaluating the protective efficacy of a trivalent vaccine containing Akabane virus, Aino virus and Chuzan virus against Schmallenberg virus infection
por: Hechinger, Silke, et al.
Publicado: (2013)

Mechanisms and Therapy for Cancer Metastasis to the Brain
por: Franchino, Federica, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_65haq84721kivl6svdm9thsr3k