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Selective anti-tumor activity of the novel fluoropyrimidine polymer F10 towards G48a orthotopic GBM tumors

F10 is a novel anti-tumor agent with minimal systemic toxicity in vivo and which displays strong cytotoxicity towards glioblastoma (GBM) cells in vitro. Here we investigate the cytotoxicity of F10 towards GBM cells and evaluate the anti-tumor activity of locally-administered F10 towards an orthotopi...

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Detalles Bibliográficos
Autores principales:	Gmeiner, William H., Lema-Tome, Carla, Gibo, Denise, Jennings-Gee, Jamie, Milligan, Carol, Debinski, Waldemar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2013
Materias:	Laboratory Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905194/ https://www.ncbi.nlm.nih.gov/pubmed/24346635 http://dx.doi.org/10.1007/s11060-013-1321-1

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