Selective increases of AMPA, NMDA, and kainate receptor subunit mRNAs in the hippocampus and orbitofrontal cortex but not in prefrontal cortex of human alcoholics

Glutamate is the main excitatory transmitter in the human brain. Drugs that affect the glutamatergic signaling will alter neuronal excitability. Ethanol inhibits glutamate receptors. We examined the expression level of glutamate receptor subunit mRNAs in human post-mortem samples from alcoholics and...

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Detalles Bibliográficos
Autores principales: Jin, Zhe, Bhandage, Amol K., Bazov, Igor, Kononenko, Olga, Bakalkin, Georgy, Korpi, Esa R., Birnir, Bryndis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905203/
https://www.ncbi.nlm.nih.gov/pubmed/24523671
http://dx.doi.org/10.3389/fncel.2014.00011

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