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Novel implications of Lingo-1 and its signaling partners in schizophrenia

Myelination and neurite outgrowth both occur during brain development, and their disturbance has been previously been implicated in the pathophysiology of schizophrenia. Leucine-rich repeat and immunoglobulin domain-containing protein (Lingo-1) is a potent negative regulator of axonal myelination an...

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Detalles Bibliográficos
Autores principales: Fernandez-Enright, F, Andrews, J L, Newell, K A, Pantelis, C, Huang, X F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905231/
https://www.ncbi.nlm.nih.gov/pubmed/24448210
http://dx.doi.org/10.1038/tp.2013.121