Cargando…

Bilateral Temporal Bone Langerhans Cell Histiocytosis: Radiologic Pearls

Langerhans cell histiocytosis (LCH) is a rare histiocytic disorder with an unpredictable clinical course and highly varied clinical presentation ranging from single system to multisystem involvement. Although head and neck involvement is common in LCH, isolated bilateral temporal bone involvement is...

Descripción completa

Detalles Bibliográficos
Autores principales: Coleman, Mira A., Matsumoto, Jane, Carr, Carrie M., Eckel, Laurence J., Nageswara Rao, Amulya A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905351/
https://www.ncbi.nlm.nih.gov/pubmed/24478812
http://dx.doi.org/10.2174/1874440001307010053
_version_ 1782301327393554432
author Coleman, Mira A.
Matsumoto, Jane
Carr, Carrie M.
Eckel, Laurence J.
Nageswara Rao, Amulya A.
author_facet Coleman, Mira A.
Matsumoto, Jane
Carr, Carrie M.
Eckel, Laurence J.
Nageswara Rao, Amulya A.
author_sort Coleman, Mira A.
collection PubMed
description Langerhans cell histiocytosis (LCH) is a rare histiocytic disorder with an unpredictable clinical course and highly varied clinical presentation ranging from single system to multisystem involvement. Although head and neck involvement is common in LCH, isolated bilateral temporal bone involvement is exceedingly rare. Furthermore, LCH is commonly misinterpreted as mastoiditis, otitis media and otitis externa, delaying diagnosis and appropriate therapeutic management. To improve detection and time to treatment, it is imperative to have LCH in the differential diagnosis for unusual presentations of the aforementioned infectious head and neck etiologies. Any lytic lesion of the temporal bone identified by radiology should raise suspicion for LCH. We hereby describe the radiologic findings of a case of bilateral temporal bone LCH, originally misdiagnosed as mastoiditis.
format Online
Article
Text
id pubmed-3905351
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Bentham Open
record_format MEDLINE/PubMed
spelling pubmed-39053512014-01-29 Bilateral Temporal Bone Langerhans Cell Histiocytosis: Radiologic Pearls Coleman, Mira A. Matsumoto, Jane Carr, Carrie M. Eckel, Laurence J. Nageswara Rao, Amulya A. Open Neuroimag J Article Langerhans cell histiocytosis (LCH) is a rare histiocytic disorder with an unpredictable clinical course and highly varied clinical presentation ranging from single system to multisystem involvement. Although head and neck involvement is common in LCH, isolated bilateral temporal bone involvement is exceedingly rare. Furthermore, LCH is commonly misinterpreted as mastoiditis, otitis media and otitis externa, delaying diagnosis and appropriate therapeutic management. To improve detection and time to treatment, it is imperative to have LCH in the differential diagnosis for unusual presentations of the aforementioned infectious head and neck etiologies. Any lytic lesion of the temporal bone identified by radiology should raise suspicion for LCH. We hereby describe the radiologic findings of a case of bilateral temporal bone LCH, originally misdiagnosed as mastoiditis. Bentham Open 2013-12-30 /pmc/articles/PMC3905351/ /pubmed/24478812 http://dx.doi.org/10.2174/1874440001307010053 Text en © Coleman et al.; Licensee Bentham Open. http://creativecommons.org/licenses/by-nc/3.0/ This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
spellingShingle Article
Coleman, Mira A.
Matsumoto, Jane
Carr, Carrie M.
Eckel, Laurence J.
Nageswara Rao, Amulya A.
Bilateral Temporal Bone Langerhans Cell Histiocytosis: Radiologic Pearls
title Bilateral Temporal Bone Langerhans Cell Histiocytosis: Radiologic Pearls
title_full Bilateral Temporal Bone Langerhans Cell Histiocytosis: Radiologic Pearls
title_fullStr Bilateral Temporal Bone Langerhans Cell Histiocytosis: Radiologic Pearls
title_full_unstemmed Bilateral Temporal Bone Langerhans Cell Histiocytosis: Radiologic Pearls
title_short Bilateral Temporal Bone Langerhans Cell Histiocytosis: Radiologic Pearls
title_sort bilateral temporal bone langerhans cell histiocytosis: radiologic pearls
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905351/
https://www.ncbi.nlm.nih.gov/pubmed/24478812
http://dx.doi.org/10.2174/1874440001307010053
work_keys_str_mv AT colemanmiraa bilateraltemporalbonelangerhanscellhistiocytosisradiologicpearls
AT matsumotojane bilateraltemporalbonelangerhanscellhistiocytosisradiologicpearls
AT carrcarriem bilateraltemporalbonelangerhanscellhistiocytosisradiologicpearls
AT eckellaurencej bilateraltemporalbonelangerhanscellhistiocytosisradiologicpearls
AT nageswararaoamulyaa bilateraltemporalbonelangerhanscellhistiocytosisradiologicpearls