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Bilateral Temporal Bone Langerhans Cell Histiocytosis: Radiologic Pearls
Langerhans cell histiocytosis (LCH) is a rare histiocytic disorder with an unpredictable clinical course and highly varied clinical presentation ranging from single system to multisystem involvement. Although head and neck involvement is common in LCH, isolated bilateral temporal bone involvement is...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Open
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905351/ https://www.ncbi.nlm.nih.gov/pubmed/24478812 http://dx.doi.org/10.2174/1874440001307010053 |
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author | Coleman, Mira A. Matsumoto, Jane Carr, Carrie M. Eckel, Laurence J. Nageswara Rao, Amulya A. |
author_facet | Coleman, Mira A. Matsumoto, Jane Carr, Carrie M. Eckel, Laurence J. Nageswara Rao, Amulya A. |
author_sort | Coleman, Mira A. |
collection | PubMed |
description | Langerhans cell histiocytosis (LCH) is a rare histiocytic disorder with an unpredictable clinical course and highly varied clinical presentation ranging from single system to multisystem involvement. Although head and neck involvement is common in LCH, isolated bilateral temporal bone involvement is exceedingly rare. Furthermore, LCH is commonly misinterpreted as mastoiditis, otitis media and otitis externa, delaying diagnosis and appropriate therapeutic management. To improve detection and time to treatment, it is imperative to have LCH in the differential diagnosis for unusual presentations of the aforementioned infectious head and neck etiologies. Any lytic lesion of the temporal bone identified by radiology should raise suspicion for LCH. We hereby describe the radiologic findings of a case of bilateral temporal bone LCH, originally misdiagnosed as mastoiditis. |
format | Online Article Text |
id | pubmed-3905351 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Bentham Open |
record_format | MEDLINE/PubMed |
spelling | pubmed-39053512014-01-29 Bilateral Temporal Bone Langerhans Cell Histiocytosis: Radiologic Pearls Coleman, Mira A. Matsumoto, Jane Carr, Carrie M. Eckel, Laurence J. Nageswara Rao, Amulya A. Open Neuroimag J Article Langerhans cell histiocytosis (LCH) is a rare histiocytic disorder with an unpredictable clinical course and highly varied clinical presentation ranging from single system to multisystem involvement. Although head and neck involvement is common in LCH, isolated bilateral temporal bone involvement is exceedingly rare. Furthermore, LCH is commonly misinterpreted as mastoiditis, otitis media and otitis externa, delaying diagnosis and appropriate therapeutic management. To improve detection and time to treatment, it is imperative to have LCH in the differential diagnosis for unusual presentations of the aforementioned infectious head and neck etiologies. Any lytic lesion of the temporal bone identified by radiology should raise suspicion for LCH. We hereby describe the radiologic findings of a case of bilateral temporal bone LCH, originally misdiagnosed as mastoiditis. Bentham Open 2013-12-30 /pmc/articles/PMC3905351/ /pubmed/24478812 http://dx.doi.org/10.2174/1874440001307010053 Text en © Coleman et al.; Licensee Bentham Open. http://creativecommons.org/licenses/by-nc/3.0/ This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited. |
spellingShingle | Article Coleman, Mira A. Matsumoto, Jane Carr, Carrie M. Eckel, Laurence J. Nageswara Rao, Amulya A. Bilateral Temporal Bone Langerhans Cell Histiocytosis: Radiologic Pearls |
title | Bilateral Temporal Bone Langerhans Cell Histiocytosis: Radiologic Pearls |
title_full | Bilateral Temporal Bone Langerhans Cell Histiocytosis: Radiologic Pearls |
title_fullStr | Bilateral Temporal Bone Langerhans Cell Histiocytosis: Radiologic Pearls |
title_full_unstemmed | Bilateral Temporal Bone Langerhans Cell Histiocytosis: Radiologic Pearls |
title_short | Bilateral Temporal Bone Langerhans Cell Histiocytosis: Radiologic Pearls |
title_sort | bilateral temporal bone langerhans cell histiocytosis: radiologic pearls |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905351/ https://www.ncbi.nlm.nih.gov/pubmed/24478812 http://dx.doi.org/10.2174/1874440001307010053 |
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