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Lead Serum Levels in Opium-Dependent Individuals
BACKGROUND: Drug abuse, especially opium abuse, is a major public health problem in Iran. Recent reports suggest that opium sellers cheat their customers by adding lead to the opium. Contaminated opium can threaten the health of consumers. The present study aimed to compare the serum level of lead b...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Kerman University of Medical Sciences
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905488/ https://www.ncbi.nlm.nih.gov/pubmed/24494092 |
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author | Hayatbakhsh Abbasi, Mohammad Mehdi Ansari, Mehdi Shahesmaeili, Armita Qaraie, Ali |
author_facet | Hayatbakhsh Abbasi, Mohammad Mehdi Ansari, Mehdi Shahesmaeili, Armita Qaraie, Ali |
author_sort | Hayatbakhsh Abbasi, Mohammad Mehdi |
collection | PubMed |
description | BACKGROUND: Drug abuse, especially opium abuse, is a major public health problem in Iran. Recent reports suggest that opium sellers cheat their customers by adding lead to the opium. Contaminated opium can threaten the health of consumers. The present study aimed to compare the serum level of lead between opium dependents and a control group. METHODS: This was a cross-sectional study in which 50 opium dependents aged 20 to 60 years old were compared with a control group of 43 non-dependents who were matched with the case group in terms of sex and age. The serum level of lead and liver function tests including serum total bilirubin, AST, ALT, Alkaline-phosphatase and hemoglobin were measured for all subjects. FINDINGS: The mean level of serum lead concentration in opium dependents and controls was 3929.358 ± 147.67 and 3532.721 ± 1141.53, respectively and the difference was not statistically significant. There was no significant correlation between serum level of lead and age, duration of opium dependency, serum total bilirubin, hemoglobin, AST, ALT, and Alkaline-phosphate. CONCLUSION: Although there was no significant relationship between opium consumption and serum level of lead, the concentration of lead in dependents' serum was higher than controls. Further studies are needed to approve this relationship to be used for screening and on time diagnosis of opium dependents. |
format | Online Article Text |
id | pubmed-3905488 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | Kerman University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-39054882014-02-03 Lead Serum Levels in Opium-Dependent Individuals Hayatbakhsh Abbasi, Mohammad Mehdi Ansari, Mehdi Shahesmaeili, Armita Qaraie, Ali Addict Health Original Article BACKGROUND: Drug abuse, especially opium abuse, is a major public health problem in Iran. Recent reports suggest that opium sellers cheat their customers by adding lead to the opium. Contaminated opium can threaten the health of consumers. The present study aimed to compare the serum level of lead between opium dependents and a control group. METHODS: This was a cross-sectional study in which 50 opium dependents aged 20 to 60 years old were compared with a control group of 43 non-dependents who were matched with the case group in terms of sex and age. The serum level of lead and liver function tests including serum total bilirubin, AST, ALT, Alkaline-phosphatase and hemoglobin were measured for all subjects. FINDINGS: The mean level of serum lead concentration in opium dependents and controls was 3929.358 ± 147.67 and 3532.721 ± 1141.53, respectively and the difference was not statistically significant. There was no significant correlation between serum level of lead and age, duration of opium dependency, serum total bilirubin, hemoglobin, AST, ALT, and Alkaline-phosphate. CONCLUSION: Although there was no significant relationship between opium consumption and serum level of lead, the concentration of lead in dependents' serum was higher than controls. Further studies are needed to approve this relationship to be used for screening and on time diagnosis of opium dependents. Kerman University of Medical Sciences 2009 /pmc/articles/PMC3905488/ /pubmed/24494092 Text en © 2009 Kerman University of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly. |
spellingShingle | Original Article Hayatbakhsh Abbasi, Mohammad Mehdi Ansari, Mehdi Shahesmaeili, Armita Qaraie, Ali Lead Serum Levels in Opium-Dependent Individuals |
title | Lead Serum Levels in Opium-Dependent Individuals |
title_full | Lead Serum Levels in Opium-Dependent Individuals |
title_fullStr | Lead Serum Levels in Opium-Dependent Individuals |
title_full_unstemmed | Lead Serum Levels in Opium-Dependent Individuals |
title_short | Lead Serum Levels in Opium-Dependent Individuals |
title_sort | lead serum levels in opium-dependent individuals |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905488/ https://www.ncbi.nlm.nih.gov/pubmed/24494092 |
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