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The phosphorylation of HIV-1 Gag by atypical protein kinase C facilitates viral infectivity by promoting Vpr incorporation into virions

BACKGROUND: Human immunodeficiency virus type 1 (HIV-1) Gag is the main structural protein that mediates the assembly and release of virus-like particles (VLPs) from an infected cell membrane. The Gag C-terminal p6 domain contains short sequence motifs that facilitate virus release from the plasma m...

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Detalles Bibliográficos
Autores principales: Kudoh, Ayumi, Takahama, Shoukichi, Sawasaki, Tatsuya, Ode, Hirotaka, Yokoyama, Masaru, Okayama, Akiko, Ishikawa, Akiyo, Miyakawa, Kei, Matsunaga, Satoko, Kimura, Hirokazu, Sugiura, Wataru, Sato, Hironori, Hirano, Hisashi, Ohno, Shigeo, Yamamoto, Naoki, Ryo, Akihide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905668/
https://www.ncbi.nlm.nih.gov/pubmed/24447338
http://dx.doi.org/10.1186/1742-4690-11-9