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Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs

Exosomes are released by most cells to the extracellular environment and are involved in cell-to-cell communication. Exosomes contain specific repertoires of mRNAs, microRNAs (miRNAs) and other non-coding RNAs that can be functionally transferred to recipient cells. However, the mechanisms that cont...

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Detalles Bibliográficos
Autores principales: Villarroya-Beltri, Carolina, Gutiérrez-Vázquez, Cristina, Sánchez-Cabo, Fátima, Pérez-Hernández, Daniel, Vázquez, Jesús, Martin-Cofreces, Noa, Martinez-Herrera, Dannys Jorge, Pascual-Montano, Alberto, Mittelbrunn, María, Sánchez-Madrid, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905700/
https://www.ncbi.nlm.nih.gov/pubmed/24356509
http://dx.doi.org/10.1038/ncomms3980