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An Update on Autoinflammatory Diseases

Autoinflammatory diseases area group of clinical conditions other than autoimmune diseases, characterized by recurrent inflammatory episodes. From apathogenetic point of view they are determined by a dys regulation of innate immunity, without involvement of specific immunity (auto reactive T cells a...

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Detalles Bibliográficos
Autores principales: Ciccarelli, F., Martinis, M. De, Ginaldi, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905709/
https://www.ncbi.nlm.nih.gov/pubmed/24164192
http://dx.doi.org/10.2174/09298673113206660303
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author Ciccarelli, F.
Martinis, M. De
Ginaldi, L.
author_facet Ciccarelli, F.
Martinis, M. De
Ginaldi, L.
author_sort Ciccarelli, F.
collection PubMed
description Autoinflammatory diseases area group of clinical conditions other than autoimmune diseases, characterized by recurrent inflammatory episodes. From apathogenetic point of view they are determined by a dys regulation of innate immunity, without involvement of specific immunity (auto reactive T cells and auto antibodies). Recently, the increased knowledge in the field of auto inflammation highlighted shared immune mechanisms in the pathogenesis of both classical monogenetic and multifactorial auto inflammatory diseases and a broad spectrum of chronic age-related inflammatory pathologies. The current increase in the prevalence of chronic inflammatory diseases makes this subject of topical interest. In the light of these considerations, we propose an update of auto inflammatory diseases and a new interpretation of auto inflammation with both theoretical and clinical implications.
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spelling pubmed-39057092014-01-29 An Update on Autoinflammatory Diseases Ciccarelli, F. Martinis, M. De Ginaldi, L. Curr Med Chem Article Autoinflammatory diseases area group of clinical conditions other than autoimmune diseases, characterized by recurrent inflammatory episodes. From apathogenetic point of view they are determined by a dys regulation of innate immunity, without involvement of specific immunity (auto reactive T cells and auto antibodies). Recently, the increased knowledge in the field of auto inflammation highlighted shared immune mechanisms in the pathogenesis of both classical monogenetic and multifactorial auto inflammatory diseases and a broad spectrum of chronic age-related inflammatory pathologies. The current increase in the prevalence of chronic inflammatory diseases makes this subject of topical interest. In the light of these considerations, we propose an update of auto inflammatory diseases and a new interpretation of auto inflammation with both theoretical and clinical implications. Bentham Science Publishers 2013-01 2013-01 /pmc/articles/PMC3905709/ /pubmed/24164192 http://dx.doi.org/10.2174/09298673113206660303 Text en Bentham Science Publishers http://creativecommons.org/licenses/by-nc/3.0/ This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
spellingShingle Article
Ciccarelli, F.
Martinis, M. De
Ginaldi, L.
An Update on Autoinflammatory Diseases
title An Update on Autoinflammatory Diseases
title_full An Update on Autoinflammatory Diseases
title_fullStr An Update on Autoinflammatory Diseases
title_full_unstemmed An Update on Autoinflammatory Diseases
title_short An Update on Autoinflammatory Diseases
title_sort update on autoinflammatory diseases
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905709/
https://www.ncbi.nlm.nih.gov/pubmed/24164192
http://dx.doi.org/10.2174/09298673113206660303
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