Maspin is not required for embryonic development or tumour suppression

Maspin (SERPINB5) is accepted as an important tumour suppressor lost in many cancers. Consistent with a critical role in development or differentiation maspin knockout mice die during early embryogenesis, yet clinical data conflict on the prognostic utility of maspin expression. Here to reconcile th...

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Detalles Bibliográficos
Autores principales: Teoh, Sonia S. Y., Vieusseux, Jessica, Prakash, Monica, Berkowicz, Susan, Luu, Jennii, Bird, Catherina H., Law, Ruby H. P., Rosado, Carlos, Price, John T., Whisstock, James C., Bird, Phillip I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905777/
https://www.ncbi.nlm.nih.gov/pubmed/24445777
http://dx.doi.org/10.1038/ncomms4164

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