Structure-function analysis of Hmo1 unveils an ancestral organization of HMG-Box factors involved in ribosomal DNA transcription from yeast to human

Ribosome biogenesis is a major metabolic effort for growing cells. In Saccharomyces cerevisiae, Hmo1, an abundant high-mobility group box protein (HMGB) binds to the coding region of the RNA polymerase I transcribed ribosomal RNAs genes and the promoters of ∼70% of ribosomal protein genes. In this s...

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Detalles Bibliográficos
Autores principales: Albert, Benjamin, Colleran, Christine, Léger-Silvestre, Isabelle, Berger, Axel B., Dez, Christophe, Normand, Christophe, Perez-Fernandez, Jorge, McStay, Brian, Gadal, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905846/
https://www.ncbi.nlm.nih.gov/pubmed/24021628
http://dx.doi.org/10.1093/nar/gkt770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905846/
https://www.ncbi.nlm.nih.gov/pubmed/24021628
http://dx.doi.org/10.1093/nar/gkt770

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