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Structure-function analysis of Hmo1 unveils an ancestral organization of HMG-Box factors involved in ribosomal DNA transcription from yeast to human
Ribosome biogenesis is a major metabolic effort for growing cells. In Saccharomyces cerevisiae, Hmo1, an abundant high-mobility group box protein (HMGB) binds to the coding region of the RNA polymerase I transcribed ribosomal RNAs genes and the promoters of ∼70% of ribosomal protein genes. In this s...
Autores principales: | Albert, Benjamin, Colleran, Christine, Léger-Silvestre, Isabelle, Berger, Axel B., Dez, Christophe, Normand, Christophe, Perez-Fernandez, Jorge, McStay, Brian, Gadal, Olivier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905846/ https://www.ncbi.nlm.nih.gov/pubmed/24021628 http://dx.doi.org/10.1093/nar/gkt770 |
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