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Co-operation of BRCA1 and POH1 relieves the barriers posed by 53BP1 and RAP80 to resection

In G2 phase cells, DNA double-strand break repair switches from DNA non-homologous end-joining to homologous recombination. This switch demands the promotion of resection. We examine the changes in 53BP1 and RAP80 ionizing radiation induced foci (IRIF) in G2 phase, as these are factors that restrict...

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Detalles Bibliográficos
Autores principales:	Kakarougkas, Andreas, Ismail, Amani, Katsuki, Yoko, Freire, Raimundo, Shibata, Atsushi, Jeggo, Penny A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905848/ https://www.ncbi.nlm.nih.gov/pubmed/24013561 http://dx.doi.org/10.1093/nar/gkt802

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