Cargando…

Structural insights into the functions of the FANCM-FAAP24 complex in DNA repair

Fanconi anemia (FA) is a genetically heterogeneous disorder associated with deficiencies in the FA complementation group network. FA complementation group M (FANCM) and FA-associated protein 24 kDa (FAAP24) form a stable complex to anchor the FA core complex to chromatin in repairing DNA interstrand...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Hui, Zhang, Tianlong, Tao, Ye, Wang, Fang, Tong, Liang, Ding, Jianping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905867/ https://www.ncbi.nlm.nih.gov/pubmed/24003026 http://dx.doi.org/10.1093/nar/gkt788

Ejemplares similares

Architecture and DNA Recognition Elements of the Fanconi Anemia FANCM-FAAP24 Complex
por: Coulthard, Rachel, et al.
Publicado: (2013)

The Fanconi anemia associated protein FAAP24 uses two substrate specific binding surfaces for DNA recognition
por: Wienk, Hans, et al.
Publicado: (2013)

Ubiquitin recognition by FAAP20 expands the complex interface beyond the canonical UBZ domain
por: Wojtaszek, Jessica L., et al.
Publicado: (2014)

Structural basis for the functional role of the Shu complex in homologous recombination
por: Zhang, Shicheng, et al.
Publicado: (2017)

Molecular basis for the substrate specificity and catalytic mechanism of thymine-7-hydroxylase in fungi
por: Li, Wenjing, et al.
Publicado: (2015)

Structural and functional characterization of the PNKP–XRCC4–LigIV DNA repair complex
por: Aceytuno, R. Daniel, et al.
Publicado: (2017)

Structural insight into repair of alkylated DNA by a new superfamily of DNA glycosylases comprising HEAT-like repeats
por: Dalhus, Bjørn, et al.
Publicado: (2007)

Structure of the mammalian adenine DNA glycosylase MUTYH: insights into the base excision repair pathway and cancer
por: Nakamura, Teruya, et al.
Publicado: (2021)

Insight into F plasmid DNA segregation revealed by structures of SopB and SopB–DNA complexes
por: Schumacher, Maria A., et al.
Publicado: (2010)

FBW7 regulates DNA interstrand cross-link repair by modulating FAAP20 degradation
por: Wang, Jingming, et al.
Publicado: (2016)

Structural basis of the XPB helicase–Bax1 nuclease complex interacting with the repair bubble DNA
por: He, Feng, et al.
Publicado: (2020)

Structural insights into recognition and repair of UV-DNA damage by Spore Photoproduct Lyase, a radical SAM enzyme
por: Benjdia, Alhosna, et al.
Publicado: (2012)

RusA Holliday junction resolvase: DNA complex structure—insights into selectivity and specificity
por: Macmaster, Rachel, et al.
Publicado: (2006)

Structural basis of the XPB–Bax1 complex as a dynamic helicase–nuclease machinery for DNA repair
por: DuPrez, Kevin, et al.
Publicado: (2020)

The crystal structure of human XPG, the xeroderma pigmentosum group G endonuclease, provides insight into nucleotide excision DNA repair
por: González-Corrochano, Rocío, et al.
Publicado: (2020)

Structural insights into VirB-DNA complexes reveal mechanism of transcriptional activation of virulence genes
por: Gao, Xiaopan, et al.
Publicado: (2013)

High FAAP24 expression reveals poor prognosis and an immunosuppressive microenvironment shaping in AML
por: Bao, Xiebing, et al.
Publicado: (2023)

Mechanistic insight into the assembly of the HerA–NurA helicase–nuclease DNA end resection complex
por: Ahdash, Zainab, et al.
Publicado: (2017)

Structural and functional insights into DNA-end processing by the archaeal HerA helicase–NurA nuclease complex
por: Blackwood, John K., et al.
Publicado: (2012)

Chromosome segregation in Archaea: SegA– and SegB–DNA complex structures provide insights into segrosome assembly
por: Yen, Cheng-Yi, et al.
Publicado: (2021)

Insights into the architecture and stoichiometry of Escherichia coli PepA•DNA complexes involved in transcriptional control and site-specific DNA recombination by atomic force microscopy
por: Minh, Phu Nguyen Le, et al.
Publicado: (2009)

Crystal structure of a KSHV–SOX–DNA complex: insights into the molecular mechanisms underlying DNase activity and host shutoff
por: Bagnéris, Claire, et al.
Publicado: (2011)

Structure and function of TatD exonuclease in DNA repair
por: Chen, Yi-Chen, et al.
Publicado: (2014)

Insights into Watson–Crick/Hoogsteen breathing dynamics and damage repair from the solution structure and dynamic ensemble of DNA duplexes containing m(1)A
por: Sathyamoorthy, Bharathwaj, et al.
Publicado: (2017)

Structural insights into the redox-switch mechanism of the MarR/DUF24-type regulator HypR
por: Palm, Gottfried J., et al.
Publicado: (2012)

Crystal structure of the UvrB dimer: insights into the nature and functioning of the UvrAB damage engagement and UvrB–DNA complexes
por: Webster, Matthew P. J., et al.
Publicado: (2012)

Structures of HIV-1 RT-RNA/DNA ternary complexes with dATP and nevirapine reveal conformational flexibility of RNA/DNA: insights into requirements for RNase H cleavage
por: Das, Kalyan, et al.
Publicado: (2014)

Crystal structures of Saccharomyces cerevisiae tryptophanyl-tRNA synthetase: new insights into the mechanism of tryptophan activation and implications for anti-fungal drug design
por: Zhou, Minyun, et al.
Publicado: (2010)

Structural insights into the duplex DNA processing of TREX2
por: Cheng, Hiu-Lo, et al.
Publicado: (2018)

Insight into formation propensity of pseudocircular DNA G-hairpins
por: Živković, Martina Lenarčič, et al.
Publicado: (2021)

Structural insights into CodY activation and DNA recognition
por: Hainzl, Tobias, et al.
Publicado: (2023)

Structural and mechanistic insights into UHRF1-mediated DNMT1 activation in the maintenance DNA methylation
por: Li, Tao, et al.
Publicado: (2018)

Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme polymerase Mu
por: Moon, Andrea F., et al.
Publicado: (2017)

DNA intercalation without flipping in the specific ThaI–DNA complex
por: Firczuk, Malgorzata, et al.
Publicado: (2011)

Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B
por: Lin, Chien-Chu, et al.
Publicado: (2020)

Structural insights into Paf1 complex assembly and histone binding
por: Chu, Xinlei, et al.
Publicado: (2013)

An ‘open’ structure of the RecOR complex supports ssDNA binding within the core of the complex
por: Radzimanowski, Jens, et al.
Publicado: (2013)

Structural insights into DNA degradation by human mitochondrial nuclease MGME1
por: Yang, Chun, et al.
Publicado: (2018)

Insights into telomeric G-quadruplex DNA recognition by HMGB1 protein
por: Amato, Jussara, et al.
Publicado: (2019)

Atomic structure of an archaeal GAN suggests its dual roles as an exonuclease in DNA repair and a CMG component in DNA replication
por: Oyama, Takuji, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_1klqaavo0l7rhteprvkuk6jk6p