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Single transcriptional and translational preQ(1) riboswitches adopt similar pre-folded ensembles that follow distinct folding pathways into the same ligand-bound structure
Riboswitches are structural elements in the 5′ untranslated regions of many bacterial messenger RNAs that regulate gene expression in response to changing metabolite concentrations by inhibition of either transcription or translation initiation. The preQ(1) (7-aminomethyl-7-deazaguanine) riboswitch...
Autores principales: | Suddala, Krishna C., Rinaldi, Arlie J., Feng, Jun, Mustoe, Anthony M., Eichhorn, Catherine D., Liberman, Joseph A., Wedekind, Joseph E., Al-Hashimi, Hashim M., Brooks, Charles L., Walter, Nils G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905878/ https://www.ncbi.nlm.nih.gov/pubmed/24003028 http://dx.doi.org/10.1093/nar/gkt798 |
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