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Helq acts in parallel to Fancc to suppress replication-associated genome instability
HELQ is a superfamily 2 DNA helicase found in archaea and metazoans. It has been implicated in processing stalled replication forks and in repairing DNA double-strand breaks and inter-strand crosslinks. Though previous studies have suggested the possibility that HELQ is involved in the Fanconi anemi...
Autores principales: | Luebben, Spencer W., Kawabata, Tsuyoshi, Akre, Monica K., Lee, Wai Long, Johnson, Charles S., O’Sullivan, M. Gerard, Shima, Naoko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905894/ https://www.ncbi.nlm.nih.gov/pubmed/24005041 http://dx.doi.org/10.1093/nar/gkt676 |
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