Structure of the human telomere in Na(+) solution: an antiparallel (2+2) G-quadruplex scaffold reveals additional diversity

Single-stranded DNA overhangs at the ends of human telomeric repeats are capable of adopting four-stranded G-quadruplex structures, which could serve as potential anticancer targets. Out of the five reported intramolecular human telomeric G-quadruplex structures, four were formed in the presence of...

Descripción completa

Detalles Bibliográficos
Autores principales: Lim, Kah Wai, Ng, Veronica Chinn Min, Martín-Pintado, Nerea, Heddi, Brahim, Phan, Anh Tuân
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905899/
https://www.ncbi.nlm.nih.gov/pubmed/23999095
http://dx.doi.org/10.1093/nar/gkt771

Ejemplares similares

Ejemplares similares