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Spiegelzymes® Mirror-Image Hammerhead Ribozymes and Mirror-Image DNAzymes, an Alternative to siRNAs and microRNAs to Cleave mRNAs In Vivo?

With the discovery of small non-coding RNA (ncRNA) molecules as regulators for cellular processes, it became intriguing to develop technologies by which these regulators can be applied in molecular biology and molecular medicine. The application of ncRNAs has significantly increased our knowledge ab...

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Detalles Bibliográficos
Autores principales: Wyszko, Eliza, Mueller, Florian, Gabryelska, Marta, Bondzio, Angelika, Popenda, Mariusz, Barciszewski, Jan, Erdmann, Volker A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906056/
https://www.ncbi.nlm.nih.gov/pubmed/24489764
http://dx.doi.org/10.1371/journal.pone.0086673