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Gene expression profiling of mesenteric lymph nodes from sheep with natural scrapie

BACKGROUND: Prion diseases are characterized by the accumulation of the pathogenic PrP(Sc) protein, mainly in the brain and the lymphoreticular system. Although prions multiply/accumulate in the lymph nodes without any detectable pathology, transcriptional changes in this tissue may reflect biologic...

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Detalles Bibliográficos
Autores principales: Filali, Hicham, Martín-Burriel, Inmaculada, Harders, Frank, Varona, Luis, Hedman, Carlos, Mediano, Diego R, Monzón, Marta, Bossers, Alex, Badiola, Juan J, Bolea, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906094/
https://www.ncbi.nlm.nih.gov/pubmed/24450868
http://dx.doi.org/10.1186/1471-2164-15-59

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