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Gene expression profiling of mesenteric lymph nodes from sheep with natural scrapie
BACKGROUND: Prion diseases are characterized by the accumulation of the pathogenic PrP(Sc) protein, mainly in the brain and the lymphoreticular system. Although prions multiply/accumulate in the lymph nodes without any detectable pathology, transcriptional changes in this tissue may reflect biologic...
Autores principales: | Filali, Hicham, Martín-Burriel, Inmaculada, Harders, Frank, Varona, Luis, Hedman, Carlos, Mediano, Diego R, Monzón, Marta, Bossers, Alex, Badiola, Juan J, Bolea, Rosa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906094/ https://www.ncbi.nlm.nih.gov/pubmed/24450868 http://dx.doi.org/10.1186/1471-2164-15-59 |
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