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Revealing Individual Signatures of Human T Cell CDR3 Sequence Repertoires with Kidera Factors
The recent development of High Throughput Sequencing technologies has enabled an individual’s TCR repertoire to be efficiently analysed at the nucleotide level. However, with unique clonotypes ranging in the tens of millions per individual, this approach gives a surfeit of information that is diffic...
Autores principales: | Epstein, Michael, Barenco, Martino, Klein, Nigel, Hubank, Michael, Callard, Robin E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906109/ https://www.ncbi.nlm.nih.gov/pubmed/24489822 http://dx.doi.org/10.1371/journal.pone.0086986 |
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