Novel Marker for the Onset of Frontotemporal Dementia: Early Increase in Activity-Dependent Neuroprotective Protein (ADNP) in the Face of Tau Mutation

Tauopathy, a major pathology in Alzheimer's disease, is also found in ∼50% of frontotemporal dementias (FTDs). Tau transcript, a product of a single gene, undergoes alternative splicing to yield 6 protein species, each with either 3 or 4 microtubule binding repeat domains (tau 3R or 4R, associa...

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Detalles Bibliográficos
Autores principales: Schirer, Yulie, Malishkevich, Anna, Ophir, Yotam, Lewis, Jada, Giladi, Eliezer, Gozes, Illana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906161/
https://www.ncbi.nlm.nih.gov/pubmed/24489906
http://dx.doi.org/10.1371/journal.pone.0087383

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