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Complementation of Essential Yeast GPI Mannosyltransferase Mutations Suggests a Novel Specificity for Certain Trypanosoma and Plasmodium PigB Proteins

The glycosylphosphatidylinositol (GPI) anchor is an essential glycolipid that tethers certain eukaryotic proteins to the cell surface. The core structure of the GPI anchor is remarkably well conserved across evolution and consists of NH(2)-CH(2)-CH(2)-PO(4)-6Manα1,2Manα1,6Manα1,4-GlcNα1,6-myo-inosit...

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Detalles Bibliográficos
Autores principales:	Cortes, Leslie K., Scarcelli, John J., Taron, Christopher H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906172/ https://www.ncbi.nlm.nih.gov/pubmed/24489949 http://dx.doi.org/10.1371/journal.pone.0087673

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