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DNA and protein co-administration induces tolerogenic dendritic cells through DC-SIGN mediated negative signals

We previously demonstrated that DNA and protein co-administration induced differentiation of immature dendritic cells (iDCs) into CD11c(+)CD40(low)IL-10(+) regulatory DCs (DCregs) via the caveolin-1 (Cav-1) -mediated signal pathway. Here, we demonstrate that production of IL-10 and the low expressio...

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Detalles Bibliográficos
Autores principales: Li, Jinyao, Geng, Shuang, Liu, Xiuping, Liu, Hu, Jin, Huali, Liu, Chang-Gong, Wang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906410/
https://www.ncbi.nlm.nih.gov/pubmed/24051433
http://dx.doi.org/10.4161/hv.25011