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Sodium fluoride disrupts DNA methylation of H19 and Peg3 imprinted genes during the early development of mouse embryo

Sodium fluoride (NaF) is associated with embryonic and fetal development abnormalities, but the mechanism by which this occurs is unclear. DNA methylation, an important epigenetic reprogramming mechanism, is essential for normal embryonic development. Thus, we investigated the effect of NaF on DNA m...

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Detalles Bibliográficos
Autores principales:	Zhu, Jia-Qiao, Si, Yang-Jun, Cheng, Lai-Yang, Xu, Bao-Zeng, Wang, Qi-Wen, Zhang, Xiao, Wang, Heng, Liu, Zong-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2013
Materias:	Inorganic Compounds
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906544/ https://www.ncbi.nlm.nih.gov/pubmed/24030355 http://dx.doi.org/10.1007/s00204-013-1122-5

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