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Mapping the AAV Capsid Host Antibody Response toward the Development of Second Generation Gene Delivery Vectors
The recombinant adeno-associated virus (rAAV) gene delivery system is entering a crucial and exciting phase with the promise of more than 20 years of intense research now realized in a number of successful human clinical trials. However, as a natural host to AAV infection, anti-AAV antibodies are pr...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906578/ https://www.ncbi.nlm.nih.gov/pubmed/24523720 http://dx.doi.org/10.3389/fimmu.2014.00009 |